The quality control department is responsible to ensure that all materials meet the established criteria throughout all phases of the process. Raw materials, components, and packaging and labeling are examined and tested according to a rigorous written program designed to assure uniformity from batch to batch. Every raw material received is tested for identity and conformance to specifications. Every bottle, cap, and the label is examined to assure that they match the written specifications.

The first step of processing every batch of product is weighing the raw materials to their proper weights indicated on the "batch production record". Highly skilled pharmacy technicians identify each raw material by its name and code number.Each raw material is weighed using a calibrated scale and placed into a clean poly-lined container that has been labeled to indicate the material, the weight, the raw material lot number, and the product name, code, and lot number of the batch being processed.

The proper handling of materials in any department is imperative to prevent any contamination or cross-contamination of the product. It is the most “crucial” stage due to the fine materials and the exposed surface area during processing. Each processing/clean room is equipped with dust collection ports to create a negative room pressure and a positive airflow out of each room to minimize the chances of cross-contamination. Highly skilled material compounders identify each of the weighed raw materials and compare them to the requirements of the "batch production record".